Tumor growth inhibition modeling to support the starting dose for dacomitinib
Abstract Dacomitinib is a second‐generation, irreversible EGFR tyrosine kinase inhibitor for first‐line treatment of patients with metastatic non‐small cell lung cancer and EGFR‐activating mutations. A high rate of dose reductions in the pivotal trial led to an observed inverse exposure‐response (ER...
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Format: | Book |
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Wiley,
2022-09-01T00:00:00Z.
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A1234.567 |
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