Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer

• المؤلفون الرئيسيون: Shengpeng Wang (مؤلف), Min Shao (مؤلف), Zhangfeng Zhong (مؤلف), Anqi Wang (مؤلف), Jiliang Cao (مؤلف), Yucong Lu (مؤلف), Yitao Wang (مؤلف), Jinming Zhang (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based combination therapy and gene therapy are new strategies to potentially overcome the limitations of TRAIL, however, the lack of efficient and low toxic vectors remains the major obstacle. In this study, we developed a hyaluronic ac...