Differential effects of Rho-kinase inhibitor and angiotensin II type-1 receptor antagonist on the vascular function in hypertensive rats induced by chronic l-NAME treatment

• Main Authors: Bainian Chen (Author), Lili Shi (Author), Xiaoyan Yu (Author), Jialin Sun (Author), Hengai Zhang (Author), Shoubao Wang (Author), Lianhua Fang (Author), Guanhua Du (Author)
• Format: Book
• Published: Elsevier, 2012-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Little attention has been paid to the effect of Rho-kinase inhibitor on the vascular dysfunction of nitric oxide-deficient hypertension. We aimed to investigate whether the Rho-kinase inhibitor fasudil showed beneficial effect on the vascular dysfunction of the NG-nitro-l-arginine methyl ester (l-NA...