Design, synthesis and antimalarial activity of novel bis{N-[(pyrrolo[1,2-a]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives

Novel series of bis- and tris-pyrrolo[1,2-a]quinoxaline derivatives 1 were synthesized and tested for in vitro activity upon the intraerythrocytic stage of W2 and 3D7 Plasmodium falciparum strains. Biological results showed good antimalarial activity with IC50 in the μM range. In attempting to inves...

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Príomhchruthaitheoirí: Jean Guillon (Údar), Anita Cohen (Údar), Nassima Meriem Gueddouda (Údar), Rabindra Nath Das (Údar), Stéphane Moreau (Údar), Luisa Ronga (Údar), Solène Savrimoutou (Údar), Louise Basmaciyan (Údar), Alix Monnier (Údar), Myriam Monget (Údar), Sandra Rubio (Údar), Timothée Garnerin (Údar), Nadine Azas (Údar), Jean-Louis Mergny (Údar), Catherine Mullié (Údar), Pascal Sonnet (Údar)
Formáid: LEABHAR
Foilsithe / Cruthaithe: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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