NMDA Receptor Glycine Binding Site Modulators for Prevention and Treatment of Ketamine Use Disorder

• Main Authors: Yu-Chin Hsiao (Author), Mei-Yi Lee (Author), Ming-Huan Chan (Author), Hwei-Hsien Chen (Author)
• 格式: 圖書
• 出版: MDPI AG, 2023-05-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Ketamine offers a fast-acting approach to relieving treatment-resistant depression, but its abuse potential is an issue of concern. As ketamine is a noncompetitive N-methyl-D-aspartate receptor (NMDAR) ion channel blocker, modulation of NMDAR might be an effective strategy to counteract the abuse li...