Survivin is essential for thermogenic program and metabolic homeostasis in mice

• Main Authors: Miriayi Alimujiang (Author), Jingjing Sun (Author), Shuqing Chen (Author), Ningning Bai (Author), Shuqin Chen (Author), Fan Hu (Author), Jingyuan Ma (Author), Yuejie Xu (Author), Jun Xu (Author), Xiaojing Ma (Author), Ying Yang (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Survivin is a member of the inhibitor of apoptosis family. Our previous study showed that survivin expression could be strongly induced by long-term, high-fat diet (HFD) exposure in vivo. It could also be induced by insulin through the PI3K/mTOR signaling pathway in vitro. Therefore, we h...