Design of drug-like hepsin inhibitors against prostate cancer and kidney stones
Hepsin, a transmembrane serine protease abundant in renal endothelial cells, is a promising therapeutic target against several cancers, particularly prostate cancer. It is involved in the release and polymerization of uromodulin in the urine, which plays a role in kidney stone formation. In this wor...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Elsevier,
2020-07-01T00:00:00Z.
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