Lutzomyia longipalpis saliva triggers lipid body formation and prostaglandin E₂ production in murine macrophages.

• Main Authors: Théo Araújo-Santos (Author), Deboraci Brito Prates (Author), Bruno Bezerril Andrade (Author), Danielle Oliveira Nascimento (Author), Jorge Clarêncio (Author), Petter F Entringer (Author), Alan B Carneiro (Author), Mário A C Silva-Neto (Author), José Carlos Miranda (Author), Cláudia Ida Brodskyn (Author), Aldina Barral (Author), Patrícia T Bozza (Author), Valéria Matos Borges (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Sand fly saliva contains molecules that modify the host's hemostasis and immune responses. Nevertheless, the role played by this saliva in the induction of key elements of inflammatory responses, such as lipid bodies (LB, also known as lipid droplets) and eicosanoids, has been poorl...