Targeting the Copper Transport System to Improve Treatment Efficacies of Platinum-Containing Drugs in Cancer Chemotherapy

• Main Authors: Macus Tien Kuo (Author), Yu-Fang Huang (Author), Cheng-Yang Chou (Author), Helen H. W. Chen (Author)
• 格式: 圖書
• 出版: MDPI AG, 2021-06-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The platinum (Pt)-containing antitumor drugs including cisplatin (cis-diamminedichloroplatinum II, cDDP), carboplatin, and oxaliplatin, have been the mainstay of cancer chemotherapy. These drugs are effective in treating many human malignancies. The major cell-killing target of Pt drugs is DNA. Rece...