Targeting the Copper Transport System to Improve Treatment Efficacies of Platinum-Containing Drugs in Cancer Chemotherapy

• Auteurs principaux: Macus Tien Kuo (Auteur), Yu-Fang Huang (Auteur), Cheng-Yang Chou (Auteur), Helen H. W. Chen (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The platinum (Pt)-containing antitumor drugs including cisplatin (cis-diamminedichloroplatinum II, cDDP), carboplatin, and oxaliplatin, have been the mainstay of cancer chemotherapy. These drugs are effective in treating many human malignancies. The major cell-killing target of Pt drugs is DNA. Rece...