P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion

P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion

Leishmaniasis is a neglected tropical disease caused by an intracellular parasite of the genus Leishmania. Damage-associated molecular patterns (DAMPs) such as UTP and ATP are released from infected cells and, once in the extracellular medium, activate P2 purinergic receptors. P2Y2 and P2X7 receptor...

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Main Authors: Maria Luiza Thorstenberg (Author), Monique Daiane Andrade Martins (Author), Vanessa Figliuolo (Author), Claudia Lucia Martins Silva (Author), Luiz Eduardo Baggio Savio (Author), Robson Coutinho-Silva (Author)
Format: Book
Published: Hindawi Limited, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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