P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion
Leishmaniasis is a neglected tropical disease caused by an intracellular parasite of the genus Leishmania. Damage-associated molecular patterns (DAMPs) such as UTP and ATP are released from infected cells and, once in the extracellular medium, activate P2 purinergic receptors. P2Y2 and P2X7 receptor...
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Main Authors: | Maria Luiza Thorstenberg (Author), Monique Daiane Andrade Martins (Author), Vanessa Figliuolo (Author), Claudia Lucia Martins Silva (Author), Luiz Eduardo Baggio Savio (Author), Robson Coutinho-Silva (Author) |
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Format: | Book |
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Hindawi Limited,
2020-01-01T00:00:00Z.
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