Enhancing In Vivo Electroporation Efficiency through Hyaluronidase: Insights into Plasmid Distribution and Optimization Strategies

• Main Authors: Debnath Maji (Author), Verónica Miguela (Author), Andrew D. Cameron (Author), Delcora A. Campbell (Author), Linda Sasset (Author), Xin Yao (Author), Andy T. Thompson (Author), Carleigh Sussman (Author), David Yang (Author), Robert Miller (Author), Marek M. Drozdz (Author), Rachel A. Liberatore (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Electroporation (EP) stands out as a promising non-viral plasmid delivery strategy, although achieving optimal transfection efficiency in vivo remains a challenge. A noteworthy advancement in the field of in vivo EP is the application of hyaluronidase, an enzyme with the capacity to degrade hyaluron...