Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein

• Main Authors: Johns Roger A (Author), Yaster Myron (Author), Zhu Xu-Guang (Author), Liaw Wen-Jinn (Author), Gauda Estelle B (Author), Tao Yuan-Xiang (Author)
• Format: Book
• Published: SAGE Publishing, 2008-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Postsynaptic density (PSD)-93, a neuronal scaffolding protein, binds to and clusters <it>N</it>-methyl-D-aspartate receptor (NMDAR) subunits NR2A and NR2B at cellular membranes <it>in vitro</it>. However, the roles of PSD-93 in synaptic NR...