Depletion of UDP-Glucose and UDP-Galactose Using a Degron System Leads to Growth Cessation of Leishmania major.

• Asıl Yazarlar: Sebastian Damerow (Yazar), Carolin Hoppe (Yazar), Giulia Bandini (Yazar), Patricia Zarnovican (Yazar), Falk F R Buettner (Yazar), Carsten G K Lüder (Yazar), Michael A J Ferguson (Yazar), Françoise H Routier (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2015-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Interconversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal) by the UDP-Glc 4´-epimerase intimately connects the biosynthesis of these two nucleotide sugars. Their de novo biosynthesis involves transformation of glucose-6-phosphate into glucose-1-phosphate by the phosphoglucomutase and subse...