Novel mechanistic study of HDAC6 regulation of rheumatoid arthritis via CMA: exploring potential therapeutic targets

• Hoofdauteurs: Duoduo Lin (Auteur), Weipeng Lai (Auteur), Ningning Zheng (Auteur), Hongbin Luo (Auteur), Xiaole Chen (Auteur), Wenzhong Que (Auteur), Nanwen Zhang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective:Rheumatoid arthritis (RA) is a systemic autoimmune disease. Its pathogenesis has not yet been clarified, so it is urgent to explore therapeutic targets. Here, we clarified the role of HDAC6 in the mechanism of action of RA through mediating chaperone-mediated autophagy (CMA) to provide a c...