Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

• Main Authors: Hongguang Sun (Author), Xun Zhu (Author), Patrick Y Lu (Author), Roberto R Rosato (Author), Wen Tan (Author), Youli Zu (Author)
• Formato: Livro
• Publicado em: Elsevier, 2014-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar to antibodies, aptamers interact with their targets by recognizing a specific three-dimensional structure and are thus...