Cost in the United States of FDA-approved small molecule protein kinase inhibitors used in the treatment of neoplastic and non-neoplastic diseases

• Autore principale: Robert Roskoski, Jr (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2024-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Because genetic alterations including mutations, overexpression, translocations, and dysregulation of protein kinases are involved in the pathogenesis of many illnesses, this enzyme family is the target of many drug discovery programs worldwide. The FDA has approved 80 small molecule protein kinase...