Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D3 Receptor Blockade

• Главные авторы: Sebastiano Alfio Torrisi (Автор), Salvatore Salomone (Автор), Federica Geraci (Автор), Filippo Caraci (Автор), Claudio Bucolo (Автор), Filippo Drago (Автор), Gian Marco Leggio (Автор)
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• Опубликовано: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Предметы: article
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Background: Several efforts have been made to develop effective antipsychotic drugs. Currently, available antipsychotics are effective on positive symptoms, less on negative symptoms, but not on cognitive impairment, a clinically relevant dimension of schizophrenia. Drug repurposing offers great adv...