Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D3 Receptor Blockade

Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D3 Receptor Blockade

Background: Several efforts have been made to develop effective antipsychotic drugs. Currently, available antipsychotics are effective on positive symptoms, less on negative symptoms, but not on cognitive impairment, a clinically relevant dimension of schizophrenia. Drug repurposing offers great adv...

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Main Authors: Sebastiano Alfio Torrisi (Author), Salvatore Salomone (Author), Federica Geraci (Author), Filippo Caraci (Author), Claudio Bucolo (Author), Filippo Drago (Author), Gian Marco Leggio (Author)
Format: Book
Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
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