Benchmarking docking, density functional theory and molecular dynamics studies to assess the aldose reductase inhibitory potential of Trigonella foenum-graecum compounds for managing diabetes-associated complications

• Main Authors: Mohammed Albratty (Author), Neelaveni Thangavel (Author), Balakumar Chandrasekaran (Author), Abdulkarim M. Meraya (Author), Hassan Ahmad Alhazmi (Author), Sankar Muthumanickam (Author), Pandi Boomi (Author), Natarajan Boopala Bhagavan (Author), Safaa F. Saleh (Author)
• Format: Book
• Published: Pensoft Publishers, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inhibition of aldose reductase (AR) could be a beneficial strategy for managing diabetes-associated complications. Trigonella foenum-graecum (TFG) is used around the globe as a traditional medicine for the management of diabetes. Our study aimed to assess the potential of TFG phytocompounds as inhib...