Targeted therapies and molecular targets in the therapeutic landscape of advanced urothelial carcinoma: state of the art and future perspectives

• Main Authors: Irene Testi (Author), Giulia Claire Giudice (Author), Giuseppe Salfi (Author), Martino Pedrani (Author), Sara Merler (Author), Fabio Turco (Author), Luigi Tortola (Author), Ursula Vogl (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Advanced urothelial carcinoma (aUC) has a dismal prognosis, with a 5-year survival rate of approximately 10%. Platinum-based chemotherapy has been the backbone of the first-line treatment of aUC for over 40 years. Only in the last decade, the treatment of aUC has evolved and been enriched with new c...