Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and Astrocytes

• Main Authors: Daisuke Watanabe (Author), Shinsuke Nakagawa (Author), Yoichi Morofuji (Author), Andrea E. Tóth (Author), Monika Vastag (Author), Jun Aruga (Author), Masami Niwa (Author), Mária A. Deli (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Culture models of the blood-brain barrier (BBB) are important research tools. Their role in the preclinical phase of drug development to estimate the permeability for potential neuropharmaceuticals is especially relevant. Since species differences in BBB transport systems exist, primate models are c...