A Humanized Monoclonal Antibody Targeting Extracellular Nicotinamide Phosphoribosyltransferase Prevents Aggressive Prostate Cancer Progression

• Main Authors: Belinda L. Sun (Author), Lin Tang (Author), Xiaoguang Sun (Author), Alexander N. Garcia (Author), Sara M. Camp (Author), Edwin Posadas (Author), Anne E. Cress (Author), Joe G. N. Garcia (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prostate cancer (PCa) is the major cause of cancer-related death in males; however, effective treatments to prevent aggressive progression remain an unmet need. We have previously demonstrated that secreted extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a multifunctional innate imm...