Recent perspectives on the relations between faecal mutagenicity, genotoxicity and diet

• Main Authors: Silvia eGratz (Author), R. John eWallace (Author), Hani eEl-Nezami (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DNA damage is an essential component of the genesis of colonic cancer. Gut microbial products and food components are thought to be principally responsible for the damage that initiates disease progression. Modified Ames tests and Comet assays have been developed for measuring mutagenicity and genot...