Blockade of 4-1BB and 4-1BBL Interaction Reduces Obesity-Induced Skeletal Muscle Inflammation

• Главные авторы: Ngoc Hoan Le (Автор), Chu-Sook Kim (Автор), Thai Hien Tu (Автор), Hye-Sun Choi (Автор), Byung-Sam Kim (Автор), Teruo Kawada (Автор), Tsuyoshi Goto (Автор), Taesun Park (Автор), Jung Han Yoon Park (Автор), Rina Yu (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2013-01-01T00:00:00Z.
• Предметы: article
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Obesity-induced skeletal muscle inflammation is characterized by increased macrophage infiltration and inflammatory cytokine production. In this study, we investigated whether 4-1BB, a member of the TNF receptor superfamily (TNFRSF9) that provides inflammatory signals, participates in obesity-induce...