Synergistic effects of a cremophor EL drug delivery system and its U0126 cargo in an ex vivo model

• Main Authors: S. T. Christensen (Author), A. S. Grell (Author), S. E. Johansson (Author), C. M. Andersson (Author), L. Edvinsson (Author), K. A. Haanes (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroprotection has proven clinically unsuccessful in subarachnoid hemorrhage. We believe that this is because the major component in the early damage pathway, the vascular wall, has not been given the necessary focus. U0126 is a potent inhibitor of vascular phenotypical changes, exemplified by func...