Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

• Main Authors: Augustin Regina (Author), Endres Kristina (Author), Reinhardt Sven (Author), Kuhn Peer-Hendrik (Author), Lichtenthaler Stefan F (Author), Hansen Jens (Author), Wurst Wolfgang (Author), Trümbach Dietrich (Author)
• Format: Book
• Published: BMC, 2012-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>MicroRNAs (miRNAs) are post-transcriptional regulators involved in numerous biological processes including the pathogenesis of Alzheimer's disease (AD). A key gene of AD, <it>ADAM10</it>, controls the proteolytic pro...