Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism

• Main Authors: Hao Wang (Author), Lin Dong (Author), Fangfei Qu (Author), Huimin He (Author), Wei Sun (Author), Yuqing Man (Author), Hongjie Jiang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Both nobiletin (NBL) and glycyrrhizin (GL) have anti-inflammatory and antitumor properties. These agents may be co-administered in the clinic. However, the drug-drug interaction between them is not clear. Objective The drug-drug interaction between GL and NBL was investigated, to clarify the...