Proteomic Analysis of Radiation-Induced Acute Liver Damage in a Rabbit Model

• Main Authors: Lingong Jiang (Author), Huimin Jia (Author), Zhicheng Tang (Author), Xiaofei Zhu (Author), Yangsen Cao (Author), Yin Tang (Author), Haiyan Yu (Author), Jianping Cao (Author), Huojun Zhang (Author), Shuyu Zhang (Author)
• Format: Book
• Published: SAGE Publishing, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiation-induced liver damage (RILD) has become a limitation in radiotherapy for hepatocellular carcinoma. We established a rabbit model of RILD by CyberKnife. Electron microscopy analysis revealed obvious nuclear atrophy and disposition of fat in the nucleus after irradiation. We then utilized a m...