An Engineered IFNγ-Antibody Fusion Protein with Improved Tumor-Homing Properties

An Engineered IFNγ-Antibody Fusion Protein with Improved Tumor-Homing Properties

Interferon-gamma (IFNγ) is one of the central cytokines produced by the innate and adaptive immune systems. IFNγ directly favors tumor growth control by enhancing the immunogenicity of tumor cells, induces IP-10 secretion facilitating (CXCR3+) immune cell infiltration, and can prime macrophages to a...

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Main Authors: Cesare Di Nitto (Author), Ettore Gilardoni (Author), Jacqueline Mock (Author), Lisa Nadal (Author), Tobias Weiss (Author), Michael Weller (Author), Frauke Seehusen (Author), Chiara Libbra (Author), Emanuele Puca (Author), Dario Neri (Author), Roberto De Luca (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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