Expression and in vitro properties of guinea pig IL-5: Comparison to human and murine orthologs

• Main Authors: Clay W Scott (Author), Carol Budzilowicz (Author), Stephen J. Hubbs (Author), Mark Stein (Author), Cindy Sobotka-Briner (Author), Deidre E. Wilkins (Author)
• Format: Book
• Published: Hindawi Limited, 2000-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin-5 (IL-5) is a key mediator of eosinophilic inflammation. The biological role of this cytokine in an allergic airway inflammatory response has been widely demonstrated in guinea pigs, yet the interaction of guinea pig IL-5 (gpIL-5) with its receptor has not been studied. Experiments were...