Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Patients with Chronic Graft-versus-Host Disease: A First-in-Human Study

• Главные авторы: Eidi Christensen (Автор), Olav A. Foss (Автор), Petter Quist-Paulsen (Автор), Ingrid Staur (Автор), Frode Pettersen (Автор), Toril Holien (Автор), Petras Juzenas (Автор), Qian Peng (Автор)
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• Опубликовано: MDPI AG, 2021-09-01T00:00:00Z.
• Предметы: article
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Extracorporeal photopheresis (ECP), an immunomodulatory therapy for the treatment of chronic graft-versus-host disease (cGvHD), exposes isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light to induce the apoptosis of T-cells and, hence, to modulate immune responses....