The beneficial effect of fluoxetine on behavioral and cognitive changes in chronic experimental Chagas disease unveils the role of serotonin fueling astrocyte infection by Trypanosoma cruzi.

• Main Authors: Glaucia Vilar-Pereira (Author), Daniel Gibaldi (Author), Leda Castaño-Barrios (Author), Andrea Alice da Silva (Author), Isabela Resende Pereira (Author), Otacílio Cruz Moreira (Author), Constança Britto (Author), Hílton Antônio Mata Dos Santos (Author), Raquel de Oliveira Lopes (Author), Luzineide Wanderley Tinoco (Author), Wilson Oliveira (Author), Joseli Lannes-Vieira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>In Chagas disease (CD), a neglected tropical disease caused by the parasite Trypanosoma cruzi, the development of mental disorders such as anxiety, depression, and memory loss may be underpinned by social, psychological, and biological stressors. Here, we investigated...