Prenatal Diagnosis of a Fetus with de novo Supernumerary Ring Chromosome 16 Characterized by Array Comparative Genomic Hybridization

• Main Authors: Pietro Cignini (Author), Angela Dinatale (Author), Laura D'Emidio (Author), Annamaria Giacobbe (Author), Elisa Maria Pappalardo (Author), Santina Ermito (Author), Domenico Bizzoco (Author), Gianluca Di Giacomo (Author), Ivan Gabrielli (Author), Alvaro Mesoraca (Author), Maurizio Giorlandino (Author), Claudio Giorlandino (Author)
• Format: Book
• Published: Thieme Medical Publishers, Inc., 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A fetus with de novo ring chromosome 16 is presented. At 20 weeks' gestation, ultrasound examination demonstrated bilateral clubfoot, bilateral renal pyelectasis, hypoplasia of the corpus callosum, and transposition of the great vessel. Amniocentesis was performed. Chromosome analysis identifie...