Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington's Disease Models: Role of PAC1 Receptor

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington's Disease Models: Role of PAC1 Receptor

Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neur...

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Main Authors: Irene Solés-Tarrés (Author), Núria Cabezas-Llobet (Author), Benjamin Lefranc (Author), Jérôme Leprince (Author), Jordi Alberch (Author), David Vaudry (Author), Xavier Xifró (Author)
Format: Book
Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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