Membrane Hyperpolarization Induced by Endoplasmic Reticulum Stress Facilitates Ca2+ Influx to Regulate Cell Cycle Progression in Brain Capillary Endothelial Cells

• Autores principales: Hiroaki Kito (Autor), Hisao Yamamura (Autor), Yoshiaki Suzuki (Autor), Susumu Ohya (Autor), Kiyofumi Asai (Autor), Yuji Imaizumi (Autor)
• Formato: Libro
• Publicado: Elsevier, 2014-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract.: Upregulation of the Kir2.1 channel during endoplasmic reticulum (ER) stress in t-BBEC117, an immortalized bovine brain endothelial cell line, caused a sustained increase in intracellular Ca2+ concentration ([Ca2+]i) and a facilitation of cell death. Expressions of Ca2+ influx channels (TR...