Brain-Targeted Delivery of Pre-miR-29b Using Lactoferrin-Stearic Acid-Modified-Chitosan/Polyethyleneimine Polyplexes

The efficacy of brain therapeutics is largely hampered by the presence of the blood-brain barrier (BBB), mainly due to the failure of most (bio) pharmaceuticals to cross it. Accordingly, this study aims to develop nanocarriers for targeted delivery of recombinant precursor microRNA (pre-miR-29b), fo...

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Main Authors: Patrícia Pereira (Author), Maria Barreira (Author), Carla Cruz (Author), Joana Tomás (Author), Ângelo Luís (Author), Augusto Q. Pedro (Author), João A. Queiroz (Author), Fani Sousa (Author)
Format: Book
Published: MDPI AG, 2020-10-01T00:00:00Z.
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