Inhibition of Pneumolysin Cytotoxicity by Hydrolysable Tannins

• Main Authors: Santeri Maatsola (Author), Sami Kurkinen (Author), Marica T. Engström (Author), Thomas K. M. Nyholm (Author), Olli Pentikäinen (Author), Juha-Pekka Salminen (Author), Sauli Haataja (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Streptococcus pneumoniae</i> causes invasive infections such as otitis media, pneumonia and meningitis. It produces the pneumolysin (Ply) toxin, which forms a pore onto the host cell membrane and has multiple functions in the pathogenesis of <i>S. pneumoniae</i>. The Ply C...