Mycobacterium tuberculosis Requires Cholesterol Oxidase to Disrupt TLR2 Signalling in Human Macrophages

This study tested the hypothesis that Mycobacterium tuberculosis (Mtb) uses a cholesterol oxidase enzyme (ChoD) to suppress a toll-like receptor type 2- (TLR2-) dependent signalling pathway to modulate macrophages' immune response. We investigated the impact of Mtb possessing or lacking ChoD as...

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Autors principals: Izabela Szulc-Kielbik (Autor), Michal Kielbik (Autor), Patrycja Przygodzka (Autor), Anna Brzostek (Autor), Jaroslaw Dziadek (Autor), Magdalena Klink (Autor)
Format: Llibre
Publicat: Hindawi Limited, 2019-01-01T00:00:00Z.
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