Can Resveratrol Influence the Activity of 11β-Hydroxysteroid Dehydrogenase Type 1? A Combined In Silico and In Vivo Study

• Auteurs principaux: Jurica Novak (Auteur), Vadim E. Tseilikman (Auteur), Olga B. Tseilikman (Auteur), Svetlana S. Lazuko (Auteur), Lyudmila E. Belyeva (Auteur), Azam Rahmani (Auteur), Julia Fedotova (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-02-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) is an NADPH-dependent reductase, responsible for the activation of cortisol by reducing cortisone. Resveratrol (RES), a type of natural polyphenol, is reported to be able to slow the progression of cancer and cardiovascular disease and i...