Pharmacogenetics and the Blood-Brain Barrier: A Whirlwind Tour of Potential Clinical Utility

• Egile Nagusiak: David R. Skvarc (Egilea), Trang T. T. Truong (Egilea), Robert M. Lundin (Egilea), Russell Barnes (Egilea), Fiona A. Wilkes (Egilea), Ajeet B. Singh (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Genetic factors influence medication response (pharmacogenetics), affecting the pharmacodynamics and pharmacokinetics of many medicaments used in clinical care. The ability of medications to cross the blood-brain barrier (BBB) represents a critical putative factor in the effectiveness and tolerabili...