Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis.

• Главные авторы: Joanna R Santos-Oliveira (Автор), Eduardo G Regis (Автор), Cássia R B Leal (Автор), Rivaldo V Cunha (Автор), Patrícia T Bozza (Автор), Alda M Da-Cruz (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2011-07-01T00:00:00Z.
• Предметы: article
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BACKGROUND: Visceral leishmaniasis (VL) is characterized by parasite-specific immunosuppression besides an intense pro-inflammatory response. Lipopolisaccharide (LPS) has been implicated in the immune activation of T-cell deficient diseases such as HIV/AIDS and idiopathic lymphocytopenia. The source...