P-glycoprotein mediated interactions between Chinese materia medica and pharmaceutical drugs

• Main Authors: Xi Yang (Author), Yuzhong Peng (Author), Yufei He (Author), Xuejun Huang (Author), Aili Xu (Author), Xiaoli Bi (Author), Ying Xie (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

P-glycoprotein (P-gp) is an important transmembrane ATP-binding cassette (ABC) drug efflux transporter expressed in various human tissues such as the intestines, liver, kidneys, and blood-brain barrier. It limits the intracellular concentration of xenobiotics by pumping them out of the cells, affect...