Synthesis and cytotoxic activity of tri-acyl ester derivatives of uridine in breast cancer cells

• Үндсэн зохиолчид: Jhon Fernando Berrío Escobar (Зохиогч), Víctor Hugo Arango Carmona (Зохиогч), Elkin Galeano Jaramillo (Зохиогч), Diana Margarita Márquez Fernández (Зохиогч), María Elena Márquez Fernández (Зохиогч), Mauricio Camargo Guerrero (Зохиогч), Alejandro Martínez Martínez (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Facultad de Farmacia, Universidad de Granada, 2016-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Aims: Synthesize tri-acyl ester derivatives of uridine, and evaluate its cytotoxicity against breast cancer cells line. Methods: The tri-esterified uridine derivatives were obtained through Steglich esterification reaction by fatty and aromatic acids, and with acetic anhydride. An acetonide derivati...