Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

• Main Authors: Margarita Parada-Kusz (Author), Cristina Penaranda (Author), Elliott J. Hagedorn (Author), Anne Clatworthy (Author), Anil V. Nair (Author), Jonathan E. Henninger (Author), Christoph Ernst (Author), Brian Li (Author), Raquel Riquelme (Author), Humberto Jijon (Author), Eduardo J. Villablanca (Author), Leonard I. Zon (Author), Deborah Hung (Author), Miguel L. Allende (Author)
• Format: Book
• Published: The Company of Biologists, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Xenografts of the hematopoietic system are extremely useful as disease models and for translational research. Zebrafish xenografts have been widely used to monitor blood cancer cell dissemination and homing due to the optical clarity of embryos and larvae, which allow unrestricted in vivo visualizat...