Development of a multiparticulate system containing enteric-release mini-tablets of omeprazole

• Main Authors: Volnei Jose Tondo Filho (Author), Itamar Francisco Andreazza (Author), Mayumi Elisa Otsuka Sato (Author), Fábio Seigi Murakami (Author)
• Format: Book
• Published: Universidade de São Paulo, 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The main aim of this study was to develop a multiparticulate system containing mini-tablets of omeprazole formulated with an enteric polymer with pH-dependent solubility. Pre-formulation studies showed good flow and compaction capacity, leading to the production ofhigh quality mini-tablets. The mini...