Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis

• Main Authors: Anna Fenzl (Author), Oana Cristina Kulterer (Author), Katrin Spirk (Author), Goran Mitulović (Author), Rodrig Marculescu (Author), Martin Bilban (Author), Sabina Baumgartner-Parzer (Author), Alexandra Kautzky-Willer (Author), Lukas Kenner (Author), Jorge Plutzky (Author), Loredana Quadro (Author), Florian W. Kiefer (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Transformation of white into brown fat ("browning") reduces obesity in many preclinical models and holds great promise as a therapeutic concept in metabolic disease. Vitamin A metabolites (retinoids) have been linked to thermogenic programming of adipose tissue; however, the phy...