Wild-type IDH2 contributes to Epstein-Barr virus-dependent metabolic alterations and tumorigenesis

• Main Authors: Feng Shi (Author), Ya He (Author), Jiangjiang Li (Author), Min Tang (Author), Yueshuo Li (Author), Longlong Xie (Author), Lin Zhao (Author), Jianmin Hu (Author), Xiangjian Luo (Author), Min Zhou (Author), Na Liu (Author), Jia Fan (Author), Jian Zhou (Author), Qiang Gao (Author), ShuangJian Qiu (Author), Weizhong Wu (Author), Xin Zhang (Author), Weihua Jia (Author), Ann M. Bode (Author), Ya Cao (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Epstein-Barr virus (EBV) is a well-recognized oncogenic virus that can induce host cell metabolic reprogramming and tumorigenesis by targeting vital metabolic enzymes or regulators. This study aims to explore the role of wild-type isocitrate dehydrogenase 2 (IDH2) in metabolic reprogrammi...