Antibody Format and Serum Disposition Govern Ocular Pharmacokinetics of Intravenously Administered Protein Therapeutics

• Main Authors: Vittal Shivva (Author), C. Andrew Boswell (Author), Hanine Rafidi (Author), Robert F. Kelley (Author), Amrita V. Kamath (Author), Susan R. Crowell (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein therapeutics have witnessed tremendous use and application in recent years in treatment of various diseases. Predicting efficacy and safety during drug discovery and translational development is a key factor for successful clinical development of these therapies. In general, drug related tox...