Transcriptional and physiological roles for STAT proteins in leptin action

• मुख्य लेखकों: Warren Pan (लेखक), Margaret B. Allison (लेखक), Paul Sabatini (लेखक), Alan Rupp (लेखक), Jessica Adams (लेखक), Christa Patterson (लेखक), Justin C. Jones (लेखक), David P. Olson (लेखक), Martin G. Myers, Jr (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2019-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objectives: Leptin acts via its receptor LepRb on specialized neurons in the brain to modulate food intake, energy expenditure, and body weight. LepRb activates signal transducers and activators of transcription (STATs, including STAT1, STAT3, and STAT5) to control gene expression. Methods: Because...