"Crying without tears" as an early diagnostic sign-post of triple A (Allgrove) syndrome: two case reports

• Hauptverfasser: Daniel Tibussek (Verfasst von), Sujal Ghosh (Verfasst von), Angela Huebner (Verfasst von), Joerg Schaper (Verfasst von), Ertan Mayatepek (Verfasst von), Katrin Koehler (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2018-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Triple A syndrome (or Allgrove syndrome) is a rare autosomal recessive disorder characterized by alacrima, achalasia, adrenal insufficiency and autonomic/neurological abnormalities. The majority of cases are caused by mutations in the AAAS gene located on chromosome 12q13. Howeve...