"Crying without tears" as an early diagnostic sign-post of triple A (Allgrove) syndrome: two case reports

• Main Authors: Daniel Tibussek (Author), Sujal Ghosh (Author), Angela Huebner (Author), Joerg Schaper (Author), Ertan Mayatepek (Author), Katrin Koehler (Author)
• Format: Book
• Published: BMC, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Triple A syndrome (or Allgrove syndrome) is a rare autosomal recessive disorder characterized by alacrima, achalasia, adrenal insufficiency and autonomic/neurological abnormalities. The majority of cases are caused by mutations in the AAAS gene located on chromosome 12q13. Howeve...